Update of P2Y receptor pharmacology: IUPHAR Review 27
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منابع مشابه
Lysophospholipid receptor nomenclature review: IUPHAR Review 8.
Lysophospholipids encompass a diverse range of small, membrane-derived phospholipids that act as extracellular signals. The signalling properties are mediated by 7-transmembrane GPCRs, constituent members of which have continued to be identified after their initial discovery in the mid-1990s. Here we briefly review this class of receptors, with a particular emphasis on their protein and gene no...
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I. Rationale for a receptor code . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271 II. Criteria for receptor characterization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273 III. Proposal for a systematic receptor code . . . . . . . . . . . . . . . . . ...
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In mammals, the endothelin (ET) family comprises three endogenous isoforms, ET-1, ET-2, and ET-3. ET-1 is the principal isoform in the human cardiovascular system and remains the most potent and long-lasting constrictor of human vessels discovered. In humans, endothelins mediate their actions via only two receptor types that have been cloned and classified as the ET(A) and ET(B) receptors in th...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2020
ISSN: 0007-1188,1476-5381
DOI: 10.1111/bph.15005